Iowa State vs. Colorado Prediction Today: College Football Week 7 Odds & Expert Pick to Win

My Iowa State vs. Colorado prediction and college football picks project coach Deion Sanders' team to defend its home field, at least as far as bettors are concerned.

Kickoff from Folsom Field in Boulder, Colo., is set for 3:30 p.m. ET (ESPN) today.

My college football predictions for Week 7 also expect Iowa State QB Rocco Becht to be unfazed on the road as a 2.5-point betting favorite today, but his team may fall short of expectations.

🏈 Iowa State vs. Colorado prediction today

College football expert picks for Week 7; odds subject to change.

• Game prediction: Colorado +2.5 (-105 via FanDuel) ⭐⭐⭐⭐
• Over/Under pick: Under 52 (-110 via Caesars) ⭐⭐⭐
• Player prop bet: Rocco Becht Over 253.5 passing yards (-114 via FanDuel) ⭐⭐⭐⭐

🆚 Who will win Iowa State vs. Colorado?

I could see Iowa State squeaking out a tight win on the road. The Cyclones have the more balanced team, ranking within the top 50 of FPI’s adjusted efficiency metrics on both offense and defense. Colorado has been strong against the spread at home, but I could see the Buffaloes falling short of an outright win against Becht’s efficient passing efforts.

Prediction: Iowa State 24, Colorado 23

💡 College football expert picks: Week 7

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• College football Week 7 schedule: What to watch

✅ Iowa State vs. Colorado expert pick

Track the latest college football scores for line movement and matchup info.

🦬 Colorado +2.5 (-105) ⭐⭐⭐⭐

Colorado’s weakness defensively has come on the ground, as the Buffaloes rank 104th in rushing yards against per game (180.2) and have surrendered 4.5 YPC (84th in FBS). But Iowa State doesn’t necessarily have the composition offensively to exploit this weakness, ranking 81st nationally in rush offense.

Colorado is 2-1-1 ATS in home games this season, while Iowa State has struggled on the road. The Cyclones are 0-2 ATS in away games, failing to cover the spread by an average margin of 9.5 points per game.

Several of our best college football betting sites, including FanDuel and DraftKings, offer Colorado +2.5 with -105 odds. The implied probability at those odds is 51.22%. A winning $10 wager on this bet would profit $9.52.

💰 Best Iowa State vs. Colorado player prop bet

Our college football player prop odds tool shows the best odds for every market across legal sportsbooks in your area.

⬆️ Rocco Becht Over 253.5 passing yards (-114) ⭐⭐⭐⭐

Though Colorado’s pass defense has only permitted two occasions of opposing quarterbacks clearing this 253.5-yard passing line against it, this Iowa State offense is more liable to attack through the air. The environment isn’t an impediment here as Iowa State has averaged 254 passing yards per road contest this season.

The Iowa State passing offense is averaging 289 yards per game over its past three games. Becht has cleared this line in three straight weeks and has gotten there in four of his past five games.

FanDuel offers the best line and odds combo on this prop (-114 odds on Over 253.5 yards). The implied probability at those odds is 53.27%. A winning $10 wager on this prop would profit $8.77.

📊 Iowa State vs. Colorado odds today

Latest college football odds updated live in real time.

📺 How to watch Iowa State vs. Colorado: Week 7

• Date: Saturday, Oct. 11
• Kickoff: 3:30 p.m. ET
• Where: Folsom Field (Boulder, Colo.)
• TV: ESPN