Bills vs. Falcons Prediction, Picks & Odds: Monday Night Football Week 6

My Bills vs. Falcons prediction expects points galore and a big night from Atlanta running back Bijan Robinson.
Bills vs. Falcons Prediction, Picks & Odds: Monday Night Football Week 6
Pictured: Bijan Robinson runs during the first half against the Washington Commanders. Photo by Brett Davis via Imagn Images

The Buffalo Bills and Atlanta Falcons clash on Monday Night Football from Mercedes-Benz Stadium (7:15 p.m. ET, ESPN), and my Bills vs. Falcons prediction backs the Over. 

The Bills are the 4 or 4.5-point betting favorite, and my NFL picks below also feature Bijan Robinson, as I expect a productive outing on the ground against one of the worst run defenses. 

For more NFL coverage, check out the NFL predictions for Week 6

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📊 Bills vs. Falcons odds: Monday Night Football

Latest Monday Night Football odds updated live in real time.


🏈 Bills vs. Falcons prediction: Monday Night Football

NFL expert picks for Monday Night Football; NFL odds subject to change.

  • Game pick: Falcons +4.5 (-115 via FanDuel) ⭐⭐⭐
  • Over/Under pick: Over 49.5 (-118 via FanDuel) ⭐⭐⭐⭐
  • Player prop bet: Bijan Robinson Over 74.5 rushing yards (-114 via FanDuel) ⭐⭐⭐⭐

✅ Bills vs. Falcons best bet for MNF

Track the latest NFL scores for line movement and matchup info.

⬆️ Over 49.5 (-118) ⭐⭐⭐⭐

The Bills are coming off a rare, ineffective offensive outing. The loss to the New England Patriots marked the first time they failed to score 30 points this season. They have scored at least 30 points in 13 of the last 16 games, with all three sub-30-point outings coming against the Patriots.

So, while the Falcons will try to follow New England's successful defensive blueprint, they will likely fail to keep them at bay.

Buffalo scored 40 and 31 points, respectively, after the previous two sub-30-point games.

The Falcons should do their part to push the total over 49.5 points, too, as they have a favorable matchup on the ground with Robinson and Tyler Allgeier facing a Bill defense with the third-worst DVOA against the run and fourth-worst EPA per run. 

🤑 Anytime touchdown bets

Looking to get a tad greedy against the Bills' run defense? Bijan Robinson's first touchdown scorer price is +440, while Tyler Allgeier is +195 to find the end zone at anytime. 

In addition, Allen averaged 40 points in his last three games where he played in similarly ideal conditions to those provided by Mercedes-Benz Stadium (Ford Field, SoFi Stadium, and LucasOil Stadium). 

FanDuel and DraftKings are the only two best sports betting sites offering a total of 49.5, with the others set at 50 points. Both offer -118 odds, which would yield an $8.47 profit. 


💰 Bills vs. Falcons player prop bet for MNF

Our NFL player prop odds tool shows the best odds for every market across legal sportsbooks in your area.

⬆️ Bijan Robinson Over 74.5 rushing yards (-114) ⭐⭐⭐⭐

Robinson hit the Over on this total in only two of four games thus far and finished with 72 yards against the Carolina Panthers. The Bills are, unenviably so, tagged with being a bottom-five rush defense in numerous categories, including DVOA (third worst), EPA per play (fourth worst), opponent yards per rush attempt (tied for second worst), and rushing yards against per game (145.6). 

FanDuel is again offering the lower total than the other best sports betting apps, which have it set at 75.5. Despite the slight buffer on the total, FanDuel's odds are the same as Caesars and better than BetMGM's (-118). 

A winning $10 bet will profit $8.77. 


How to watch Monday Night Football

  • Matchup: Bills vs. Falcons
  • When: Monday, Oct. 13
  • Time: 7:15 p.m. ET
  • Where: Mercedes-Benz Stadium (Atlanta)
  • TV: ESPN

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