NFL Preseason Week 2 Predictions 2025: Best Odds & Bets for All 16 Games

Our NFL Preseason Week 2 Predictions feature all 16 games and include the updated odds.

Gary Pearson

Last Updated: August 12, 2025 6:13 AM EDT • 3 minute read

NFL Preseason Week 2 Predictions 2025: Odds, Expert Picks for Every Game — Pictured: Jalen Milroe hands the ball off to running back Anthony Tyus as we offer our NFL Preseason Week 2 Predictions. Photo by Steven Bisig via Imagn Images

We're just two days away from another full slate of games as we offer NFL preseason Week 2 predictions, which feature updated odds from our best sports betting sites.

Friday's double bill features the Atlanta Falcons vs. Tennessee Titans and Seattle Seahawks vs. Kansas City Chiefs, with the docket culminating on Monday night when the Cincinnati Bengals face the Washington Commanders.

We're also on rookie watch after evaluating how the OROY contenders performed.

🏈 NFL predictions for preseason Week 2

🔎 Our NFL player prop odds tool can help you find the best NFL odds to make your NFL picks across legal sportsbooks in your region.

Titans vs. Falcons prediction (coming soon)
Chiefs vs. Seahawks prediction (coming soon)
Browns vs. Eagles prediction (coming soon)
49ers vs. Raiders prediction (coming soon)
Jets vs. Giants prediction (coming soon)
Cardinals vs. Broncos prediction (coming soon)
Jaguars vs. Saints prediction (coming soon)
Bills vs. Bears prediction (coming soon)
Bengals vs. Commanders prediction (coming soon)

📖 Check out our 2025 NFL preseason betting guide for our best betting strategies and full NFL preseason schedule.

💰 NFL preseason odds & expert picks: Week 2

Here are the latest odds for every game via the best NFL betting sites, which update live in real time. Follow the latest NFL scores for line history and matchup info.

📊 Titans vs. Falcons odds

Date: Friday, Aug. 15
Kickoff: 7 p.m. ET
Location: Mercedes-Benz Stadium (Atlanta)
How to watch: NFL Network

📊 Chiefs vs. Seahawks odds

Date: Friday, Aug. 15
Kickoff: 10 p.m. ET
Location: Lumen Stadium (Seattle)
How to watch: NFL Network

📊 Dolphins vs. Lions odds

Date: Saturday, Aug. 16
Kickoff: 1 p.m. ET
Location: Ford Field (Detroit)
How to watch: FOX

📊 Packers vs. Colts odds

Date: Saturday, Aug. 16
Kickoff: 1 p.m. ET
Location: Lucas Oil Stadium (Indianapolis)
How to watch: ABC, CBS

📊 Patriots vs. Vikings odds

Date: Saturday, Aug. 16
Kickoff: 1 p.m. ET
Location: U.S. Bank Stadium (Minneapolis)
How to watch: NFL Network

📊 Browns vs. Eagles odds

Date: Saturday, Aug. 16
Kickoff: 1 p.m. ET
Location: Lincoln Financial Field (Philadelphia)
How to watch: NFL Network

📊 Panthers vs. Texans odds

Date: Saturday, Aug. 16
Kickoff: 1 p.m. ET
Location: NRG Stadium (Houston)
How to watch: ABC

📊 49ers vs. Raiders odds

Date: Saturday, Aug. 16
Kickoff: 4 p.m. ET
Location: Allegiant Stadium (Las Vegas)
How to watch: NFL Network

📊 Ravens vs. Cowboys odds

Date: Saturday, Aug. 16
Kickoff: 7 p.m. ET
Location: AT&T Stadium (Arlington, Texas)
How to watch: NFL Network

📊 Chargers vs. Rams odds

Date: Saturday, Aug. 16
Kickoff: 7 p.m. ET
Location: SoFi Stadium (Inglewood, Calif.)
How to watch: ABC

📊 Jets vs. Giants odds

Date: Saturday, Aug. 16
Kickoff: 7 p.m. ET
Location: MetLife Stadium (East Rutherford, N.J.)
How to watch: NFL Network

📊 Buccaneers vs. Steelers odds

Date: Saturday, Aug. 16
Kickoff: 7 p.m. ET
Location: Acrisure Stadium (Pittsburgh)
How to watch: FOX

📊 Cardinals vs. Broncos odds

Date: Saturday, Aug. 16
Kickoff: 9:30 p.m. ET
Location: Empower Field at Mile High (Denver)
How to watch: NFL Network

📊 Jaguars vs. Saints odds

Date: Sunday, Aug. 17
Kickoff: 1 p.m. ET
Location: Caesars Superdome (New Orleans)
How to watch: NFL Network

📊 Bills vs. Bears odds

Date: Sunday, Aug. 17
Kickoff: 8 p.m. ET
Location: Soldier Stadium (Chicago)
How to watch: NBC

📊 Bengals vs. Commanders odds

Date: Monday, Aug. 18
Kickoff: 8 p.m. ET
Location: Northwest Stadium (Landover, Md.)
How to watch: ESPN, ABC

🔢 NFL betting odds pages

Super Bowl Odds	NFL MVP Odds	NFL Offensive Player of the Year Odds
NFL Defensive Player of the Year Odds	NFL Offensive Rookie of the Year Odds	NFL Defensive Rookie of the Year Odds
NFL Coach of the Year Odds	NFL Comeback Player of the Year Odds	NFL Win Totals Odds
NFL Playoff Odds	NFL Draft Odds

❓ NFL betting FAQs

What does the spread mean in betting NFL?

In NFL betting, the spread is the number of points a team is favored to win or lose by. It levels the playing field for bettors by giving an advantage or disadvantage in points. Bettors win if their pick covers the spread.

Where can I find top NFL betting odds?

Make sure you look at our top NFL betting sites to find the best odds for NFL Sunday. These sportsbooks include Caesars, BetMGM, bet365, FanDuel, and DraftKings.

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Written by:
Gary Pearson

Gary Pearson has written professionally since 2010, focusing on sports betting since 2014. Before entering the sports betting space, he contributed to the Canadian Press, FanSided, the Hockey Writers, the Calgary Herald, and other publications. His work has also been featured in Sports Illustrated and Bleacher Report. Gary, who consumes sports like a blue whale devours plankton, has a penchant for writing predictions and analyses across several sports, including hockey, soccer, football, tennis, and more. He bets regularly, preferring single-game picks, props, and live betting. While there isn't a sport he has yet to dabble in, Gary prefers betting on soccer, hockey, and football. He studied at various post-secondary institutions, including the University of Calgary, SAIT Polytechnic, and Griffith University, located in Brisbane, Australia. Gary has a marketing degree and completed his bachelor's degree in journalism at Griffith University. He feels strongly that life experience is as essential as post-secondary education, helping formulate more accurate predictions and analyses. Gary believes that competing at a high level of amateur sports during his formative years helped him better understand an athlete's psyche and the nuances and complexities of a team's dynamic, both on and off the playing surface. He feels that knowledge is immeasurably important when offering his analytical expertise. He has lived on five continents and currently resides in Canada.

Falcons vs. Titans Prediction, Odds & Expert Picks: NFL Preseason Week 2